Thursday, 28 July 2011

Avandia, a Diabetes Medicine Information You Should Know About

Avandia and its uses

Avandia is drug to treat non-insulin dependent diabetes or diabetes type 2. Rosiglitazone maleate is generic equivalent of avandia. Avandia lowers sugar level in blood. It is so far the most successful medicine to treat diabetes mellitus type 2 with lesser side effects as compare to other diabetes drugs. It enables the body to consume glucose by producing more insulin. By interfering process of glucose formation, avandia also lowers the production of glucose.

Avandia should be administered along with diet and exercise suggested by physician.

Avandia acts in two ways to maintain blood sugar level in body.

* Produces insulin so that glucose can be consumed by cells.
*Maintains good functionality of mast cells.

For overweight diabetic patients avandia may also be used with metformin (Avandamet). For patients allergic to metformin are given avandia in combination with sulphonylurea (Amaryl). In rare cases it may be given with metformin and sulphonylurea.

Working Mechanism

Avandia is used when mast cells of pancreas are unable to produce enough insulin. Insulin is key hormone helpfull to break down glucose and generate energy. Lack of insulins cause to increase glucose level in blood. Rosiglitazone maleate helps mast cells to produce more insulin. It also ensures good functionality of mast cells.

Contraindications

Avandia is contraindicated if....
  • Patient is allergic to any of its ingredients
  • Insulin treatment is going on
  • Recent history of heart failure
  • Pregnancy and breastfeeding

Interactions

Before start taking avandia you should know these.....

Avandia may increase weight. As stated earlier avandia should be taken with proper (calorie controlled) diet.
Patients with heart related problem in past should not take this medicine. Patients with no heart issue in past should consult doctor in case short breath and rapid weight gain.

Avandia may increase risk of fluid retention if taken with non-steroidal anti-inflammatory drugs such as ibuprofen or diclofenac.

Below list of drugs may decrease efectiveness of avandia by lowring its presense in blood.
  • carbamazepine
  • rifampicin
  • phenobarbital
  • phenytoin

Side Effects

Avandia shows least side effects compare to other diabetes drugs.
  • Abnormal liver function
  • vision problem (blurred vision)
  • weight gain
  • Headache
  • Tiredness
  • Dizziness
  • Low blood glucose level (hypoglycaemia)
  • Swelling because of fluid retention
  • heart failure

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